Spectrophotometric determination of quetiapine fumarate in pharmaceuticals and human urine by two charge-transfer complexation reactions
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Sensitive ultraviolet spectrophotometric determination of quetiapine fumarate in pharmaceuticals
Quetiapine fumarate (QTF) is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives indicated for the treatment of schizophrenia. It is a selective monoaminergic antagonist with high affinity for the serotonin type 2 (5HT2), and dopamine type 2 (D2) receptors. Two simple, sensitive, selective, economical and reproducible UV spectrophotometric methods are described for...
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This is the first report on use of two visible spectrophotometric methods for the determination of bupropion hydrochloride (BUPH) in pharmaceuticals and spiked human urine. Bupropion is a second-generation antidepressant agent which is also used in the management of smoking cessation. The methods are based on charge transfer complexation reaction of bupropion base (BUP) as n-electron donor with...
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Article history: Received on: 07/09/2013 Revised on: 19/09/2013 Accepted on: 23/11/2013 Available online: 29/11/2013 This work presents two simple and direct spectrophotometric methods for determination of rabeprazole sodium (RB) through charge transfer complexation reactions. The first method is based on the reaction of the drug with p-chloranilic acid (p-CA) in acetonitrile to give a red colo...
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Metformin hydrochloride (MFH) is an oral anti-diabetic drug of biguanide class. Two selective spectrophotometric methods were presented for the determination of MFH in pharmaceuticals. The methods were based on the measurement of yellow-coloured charge-transfer complexes formed between MFH and two poly-nitrophenols, namely, 2,4-dinitrophenol (DNP method, at 405 nm) and picric acid (PA met...
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Three simple and sensitive spectrophotometric methods are described for the determination of ofloxacin (OFX) in pharmaceuticals and in spiked human urine. First and second methods are based on the measurement of absorbance of OFX in 0.1 M HCl at 293 nm (method A) and 0.1 M NaOH at 287 nm, respectively. The third method is based on the measurement of 2:1 complex formed between OFX and iron(III) ...
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ژورنال
عنوان ژورنال: Chemical Industry and Chemical Engineering Quarterly
سال: 2012
ISSN: 1451-9372,2217-7434
DOI: 10.2298/ciceq111006003v